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ENDOMETRIOSI - Dalla ricerca nuove prospettive per comprendere la malattia

congresso 20170127 180Endometriosi. Una malattia talora devastante che colpisce 176 milioni di donne nel mondo. Una malattia che coinvolge, negativamente, tanti aspetti della vita della donna. Una malattia che ha impegnato per anni, e tuttora impegna, moltissimi ricercatori e clinici. Una malattia che ancora oggi, però, viene definita come “enigmatica”. In questo convegno vogliamo tentare di capire.

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AOGOI 20-21 Novembre 2014 - Bergamo

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Scanzorosciate: Ændo e Sichig

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Pubblicazioni - - Leisure and occupational physical activity at different ages and risk of endometriosis PDF Stampa E-mail
Indice
Pubblicazioni
- Peculiar aspects of endometriosis in adolescents, Journal of Endometriosis 2010; 2(1): 19 - 25
- Diet and endometriosis risk: aliterature review. Reprod Biomed Online. 2013 Apr;26(4):323-36.
- An Italian association study and meta-analysis with previous GWAS confirm WNT4, CDKN2BAS and FN1 as the first identified susceptibility loci for endometriosis. J Med Genet. 2013 Jan;50(1):43-6.
- The molecular connections between the cannabinoid system and endometriosis. Mol Hum Reprod. 2012 Dec;18(12):563-71.
- The distinguishing cellular and molecular features of the endometriotic ovarian cyst: from pathophysiology to the potential endometrioma-mediated damage to the ovary. Hum Reprod Update. 2013 Oct 14.
- Coffee and caffeine intake and risk of endometriosis: a meta-analysis. Eur J Nutr. 2014 Oct;53(7):1573-9. doi: 10.1007/s00394-014-0662-7. Epub 2014 Jan 31
- External Validation of the Endometriosis Fertility Index (EFI) for Predicting Spontaneous Pregnancy after Surgery: Further Considerations on Its Validity
- Leisure and occupational physical activity at different ages and risk of endometriosis
- The Targeted Delivery of Interleukin 4 Inhibits Development of Endometriotic Lesions in a Mouse Model
- World Endometriosis Society consensus on the classification of endometriosis
- Fruit and vegetable consumption and risk of endometriosis
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- E. Garavaglia a, E. Ricci b,*, F. Chiaffarino b, S. Cipriani b, R. Cioffi a, P. Vigano` c, A. Frigerio b, M. Candiani a, F. Parazzini b

a Obstetrics and Gynecology Unit, San Raffaele Scientific Institute, Milan, Italy
b Dipartimento di Scienze Cliniche e di Comunita`, Universita` di Milano, Fondazione IRCCS Ca’ Granda—Ospedale Maggiore Policlinico, Milan, Italy
c Reproductive Sciences Laboratory, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy

 

"Leisure and occupational physical activity at different ages and risk of endometriosis"

Article history: Received 12 June 2014; Received in revised form 8 October 2014; Accepted 22 October 2014

 

A B S T R A C T
Objective: Cohort and case-control studies have suggested that adult physical activity (PA) may lower endometriosis risk and improve symptoms, but evidence is still controversial. To add information on
leisure and occupational PA impact, if any, on endometriosis risk, we have analyzed data from a small case-control study conducted in Milan (Italy).
Study design: Ninety cases and 90 controls (median age 35 years, range 18–76) were compared.
Endometriosis was laparoscopically diagnosed within the year before interview.
Information on demographic variables, menstrual and reproductive history, occupational and recreational physical activity was collected.
Results: A consistent protective effect emerged between leisure PA and endometriosis risk. For <2–4 and 5 h/week (reference no PA), the estimated odds ratios (ORs) were, respectively: 0.36 (95% CI 0.18–0.74) and 0.83 (95% CI 0.27–2.53) as regards PA in early adolescence; 0.31 (95% CI 0.15–0.63) and 0.78 (95% CI
0.25–2.38) as regards PA in teenage years; 0.34 (95% CI 0.12–0.94) and 0.33 (95% CI 0.08–1.28) for PA in adulthood.
However, no significant trend was seen according to hours spent in leisure PA. Occupational PA did not show statistical significant differences among different types or across age classes.
Conclusions: These results suggest that leisure PA in early adolescence, teenage years and adulthood may, to some extent, decrease the risk of endometriosis.
In the interpretation of these results, however, the role of potential biases cannot be totally ruled out.
2014 Elsevier Ireland Ltd. All rights reserved.

 



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